Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245119 | 1.00 | SIGMAR1 (0.55) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL25253831 | 0.93 | SIGMAR1 (0.57) | SIGMAR1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL30245727 | 0.93 | SIGMAR1 (0.57) | SIGMAR1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL30245819 | 0.93 | SIGMAR1 (0.63) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL25255754 | 0.93 | SIGMAR1 (0.63) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL25297695 | 0.91 | ALDH1A1 (0.53) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30245399 | 0.91 | ALDH1A1 (0.53) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30245208 | 0.89 | SMN1; SMN2 (0.52) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30245758 | 0.89 | SIGMAR1 (0.63) | SIGMAR1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL25248944 | 0.86 | KDM4E (0.57) | SIGMAR1KDM4EALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |