Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529979 | 0.92 | FAAH (0.39) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL2529889 | 0.90 | FAAH (0.41) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL2529975 | 0.90 | FAAH (0.41) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL5021516 | 0.85 | FAAH (0.40) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL16640759 | 0.85 | FAAH (0.46) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL12247043 | 0.82 | FAAH (0.48) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL16722811 | 0.82 | FAAH (0.48) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL19163900 | 0.82 | FAAH (0.48) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL13661862 | 0.82 | FAAH (0.48) | FAAHCES1CES2KMT2AMEN1 | |
| SCHEMBL2528459 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |