Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | HPGD | P15428 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25862420 | 1.00 | CACNA2D1 (0.42) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25296656 | 1.00 | CACNA2D1 (0.42) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25294628 | 0.86 | CACNA2D1 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25862416 | 0.86 | CACNA2D1 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25294629 | 0.86 | CACNA2D1 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30488570 | 0.86 | CACNA2D1 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30488545 | 0.84 | TNK2 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL30488495 | 0.84 | TNK2 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29030601 | 0.84 | TNK2 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25862365 | 0.84 | TNK2 (0.41) | CACNA2D1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250152584-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2025-05-15 | — | — | US | disclosed |
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| EP-4461729-A1 | ANTIGEN BINDING PROTEIN TARGETING MSLN AND USE THEREOF | Transthera Sciences (Nanjing), Inc. (CN) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250152584-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | NLRP3, NLRP1, PYCARD | CACNA2D1 3026/4885ALDH1A1 3156/4885HPGD 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.