SCHEMBL25257345

SCHEMBL25257345

O=C(Oc1ccc(-c2ccccc2)cc1)Oc1ccc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 2/20 0.47
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
BACE1 P56817 5/20 0.41
PTGDR2 Q9Y5Y4 4/20 0.40
FABP7 O15540 1/20 0.40
FABP3 P05413 1/20 0.40
FABP5 Q01469 1/20 0.40
EGFR P00533 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17697650 0.93 SLC6A9 (0.51) SLC6A9MAPTLMNAKMT2AMEN1
SCHEMBL17697669 0.87 FABP3 (0.48) TDP1LMNAGAAKMT2AMEN1
SCHEMBL10429597 0.84 LMNA (0.60) SLC6A9MAPTTDP1LMNAGAA
SCHEMBL17709397 0.84 KDM4E (0.50) SLC6A9MAPTLMNAKMT2AMEN1
SCHEMBL17697651 0.83 SLC6A9 (0.51) SLC6A9MAPTLMNAKMT2AMEN1
SCHEMBL233643 0.82 KMT2A (0.55) MAPTTDP1LMNAGAAKMT2A
SCHEMBL236824 0.82 KMT2A (0.55) MAPTTDP1LMNAGAAKMT2A
SCHEMBL24575151 0.81 ELANE (0.55) SLC6A9MAPTTDP1LMNAGAA
SCHEMBL246849 0.80 KMT2A (0.53) MAPTTDP1LMNAGAAKMT2A
SCHEMBL10429619 0.80 BACE1 (0.61) SLC6A9MAPTTDP1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed