Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.34 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245771 | 1.00 | CETP (0.37) | CETPQPCTHRH3F10CNR1 | |
| SCHEMBL30245083 | 0.94 | KIT (0.39) | CETPQPCTF10ABCB1KIT | |
| SCHEMBL29194746 | 0.94 | KIT (0.39) | CETPQPCTF10ABCB1KIT | |
| SCHEMBL30245826 | 0.94 | QPCT (0.37) | CETPQPCTHRH3F10LTA4H | |
| SCHEMBL25260059 | 0.94 | QPCT (0.37) | CETPQPCTHRH3F10LTA4H | |
| SCHEMBL30245935 | 0.94 | FGFR1 (0.42) | CETPQPCTF10FGFR1KDR | |
| SCHEMBL29194558 | 0.94 | FGFR1 (0.42) | CETPQPCTF10FGFR1KDR | |
| SCHEMBL25253113 | 0.91 | QPCT (0.41) | CETPQPCTHRH3F10CNR1 | |
| SCHEMBL30245239 | 0.91 | QPCT (0.41) | CETPQPCTHRH3F10CNR1 | |
| SCHEMBL25251894 | 0.90 | CETP (0.40) | CETPQPCTHRH3CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023018472-A9 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | TEXAS HEART INSTITUTE (US) | 2023-07-13 | — | — | WO | disclosed |