Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30245083 | 1.00 | KIT (0.39) | KITVNN1CETPABCB1MAPKAPK2 | |
| SCHEMBL30245771 | 0.94 | CETP (0.37) | KITCETPABCB1QPCTF10 | |
| SCHEMBL30245164 | 0.94 | NPC1 (0.38) | KITABCB1QPCTFLT3JAK2 | |
| SCHEMBL25296124 | 0.94 | NPC1 (0.38) | KITABCB1QPCTFLT3JAK2 | |
| SCHEMBL25257583 | 0.94 | CETP (0.37) | KITCETPABCB1QPCTF10 | |
| SCHEMBL29194558 | 0.93 | FGFR1 (0.42) | KITCETPQPCTFLT3F10 | |
| SCHEMBL30245935 | 0.93 | FGFR1 (0.42) | KITCETPQPCTFLT3F10 | |
| SCHEMBL30245554 | 0.91 | VNN1 (0.43) | KITVNN1CETPABCB1MAPKAPK2 | |
| SCHEMBL25259271 | 0.90 | KIT (0.42) | KITVNN1CETPABCB1QPCT | |
| SCHEMBL30246077 | 0.90 | KIT (0.42) | KITVNN1CETPABCB1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |