Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581426 | 0.92 | MAPT (0.65) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL25257088 | 0.92 | MAPT (0.65) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL25254166 | 0.77 | MAPT (0.61) | MAPTL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL13497817 | 0.76 | MAPT (0.53) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL25258715 | 0.75 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL9682067 | 0.75 | MAPT (0.76) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL16043208 | 0.75 | MAPT (0.53) | MAPTL3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL13331973 | 0.75 | HTR6 (0.56) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL9682931 | 0.75 | MAPT (0.58) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL2475101 | 0.75 | MAPT (0.56) | MAPTL3MBTL1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401531-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |