Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581459 | 0.91 | MAPT (0.74) | MAPTMEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL25257373 | 0.91 | MAPT (0.74) | MAPTMEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL25258767 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL6832159 | 0.72 | HSP90AA1 (0.63) | MAPTMEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL25296914 | 0.72 | MAPT (0.49) | MAPTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7102632 | 0.71 | CYP3A4 (0.52) | MAPTKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16044561 | 0.71 | AGER (0.56) | MAPTMEN1KMT2AL3MBTL1HSP90AA1 | |
| SCHEMBL9682901 | 0.71 | MAPT (0.43) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL14847556 | 0.71 | MAPT (0.43) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13332614 | 0.71 | KMT2A (0.51) | MAPTMEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401531-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |