SCHEMBL25258809

SCHEMBL25258809

Nc1ccc(C(F)(F)F)c(Oc2ccc(C3(c4ccc(Oc5cc(N)ccc5C(F)(F)F)c(-c5ccccc5)c4)c4ccccc4-c4ccccc43)cc2-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AR P10275 1/20 0.38
PDK2 Q15119 5/20 0.38
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
PTGDR2 Q9Y5Y4 2/20 0.35
SCN9A Q15858 3/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6138360 0.92 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418459 0.92 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2448288 0.85 ESR1 (0.44) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25218458 0.84 AR (0.38) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25269471 0.83 AR (0.45) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25269880 0.83 AR (0.47) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418329 0.83 AR (0.45) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25217980 0.83 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25218598 0.83 KDM4E (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446258 0.82 KDM4E (0.50) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed