Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586455 | 1.00 | GAA (0.44) | GAAKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL25262670 | 0.90 | SMN1; SMN2 (0.44) | GAAKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL30586457 | 0.90 | SMN1; SMN2 (0.44) | GAAKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL30586478 | 0.87 | CA2 (0.44) | GAAKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL25257071 | 0.87 | CA2 (0.44) | GAAKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL29036924 | 0.80 | HSD17B2 (0.39) | KDM4EALDH1A1HPGDMAPK1STING1 | |
| SCHEMBL25253344 | 0.78 | CA2 (0.43) | ALDH1A1USP2NPSR1TSHRLMNA | |
| SCHEMBL30586476 | 0.78 | CA2 (0.43) | ALDH1A1USP2NPSR1TSHRLMNA | |
| SCHEMBL25826736 | 0.78 | ENPP1 (0.70) | STING1ENPP1 | |
| SCHEMBL25259879 | 0.78 | STING1 (0.47) | STING1ENPP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444544-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2023-07-18 | — | — | CN | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |