Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21681168 | 0.79 | KDM4E (0.46) | XDHKMOKDM4EL3MBTL1LMNA | |
| SCHEMBL28448915 | 0.77 | GRM4 (0.49) | ALDH1A1KMOGRK6GRM4 | |
| SCHEMBL19876647 | 0.77 | CLK4 (0.52) | ALDH1A1GRM4PDGFRBPDGFRAKDM4E | |
| SCHEMBL21271882 | 0.76 | MAP4K1 (0.55) | PDGFRB | |
| SCHEMBL29572632 | 0.76 | MAP4K1 (0.55) | PDGFRB | |
| SCHEMBL26058396 | 0.76 | MAP4K1 (0.38) | XDHALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL28988552 | 0.75 | XDH (0.56) | XDHKDM4EL3MBTL1RAB9A | |
| SCHEMBL30459434 | 0.75 | KMO (0.72) | KMO | |
| SCHEMBL24243059 | 0.75 | KMO (0.72) | KMO | |
| SCHEMBL30103118 | 0.75 | PHF8 (0.40) | GRK6PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192819-A1 | HETEROBIARYL COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |