Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25842016 | 0.81 | TGFBR1 (0.40) | IDO1TGFBR1MAPK14ACVR1B | |
| SCHEMBL25842013 | 0.80 | MAPK14 (0.40) | IDO1CYP3A4TGFBR1MAPK14MAPK13 | |
| SCHEMBL25302190 | 0.79 | SYK (0.44) | SYKKDM4ECYP3A4MAPTTGFBR1 | |
| SCHEMBL30387353 | 0.77 | BRAF (0.42) | SYKKDM4ECYP3A4MAPTTGFBR1 | |
| SCHEMBL25302657 | 0.77 | BRAF (0.42) | SYKKDM4ECYP3A4MAPTTGFBR1 | |
| SCHEMBL30139830 | 0.77 | TGFBR1 (0.55) | IDO1KDM4ECYP3A4MAPTTGFBR1 | |
| SCHEMBL15188295 | 0.77 | TGFBR1 (0.57) | KDM4ECYP3A4MAPTTGFBR1MAPK14 | |
| SCHEMBL30635236 | 0.74 | KDM4E (0.50) | KDM4ECYP3A4MAPTTGFBR1NPY5R | |
| SCHEMBL23418795 | 0.70 | TNIK (0.41) | IDO1KDM4ECYP3A4MAPTTGFBR1 | |
| SCHEMBL25822608 | 0.70 | IDO1 (0.45) | IDO1KDM4ECYP3A4MAPTTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12473274-B2 | Heterocyclic compound as inhibitor of casein kinase 1-δ and/or activin receptor-like kinase 5 | ALCHEMEDICINE, INC. (JP) | 2025-11-18 | — | — | US | disclosed |
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | ALCHEMEDICINE, INC. (JP) | 2023-06-15 | — | — | US | disclosed |
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | ALCHEMEDICINE, INC. (JP) | 2023-06-15 | — | — | US | disclosed |
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | ALCHEMEDICINE, INC. (JP) | 2023-06-15 | — | — | US | disclosed |
| EP-4174061-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR FOR CASEIN KINASE 1d AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | Alchemedicine, Inc. (JP) | 2023-05-03 | — | — | EP | disclosed |
| EP-4174061-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR FOR CASEIN KINASE 1d AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | Alchemedicine, Inc. (JP) | 2023-05-03 | — | — | EP | disclosed |
| CN-116034105-A | Heterocyclic compounds as inhibitors of casein kinase 1 delta and/or activin receptor-like kinase 5 | 亚克医药株式会社 | 2023-04-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183220-A1 | HETEROCYCLIC COMPOUND AS INHIBITOR OF CASEIN KINASE 1-DELTA AND/OR ACTIVIN RECEPTOR-LIKE KINASE 5 | CSNK1A1, CSNK1G1, CSNK1D | SYK 1739/4885IDO1 633/4885KDM4E 1022/4885 |
| US-12473274-B2 | Heterocyclic compound as inhibitor of casein kinase 1-δ and/or activin receptor-like kinase 5 | CSNK1A1, CSNK1G1, CKS1B | SYK 1743/4885IDO1 578/4885KDM4E 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.