Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.40 |
| ▸ | IL1B | P01584 | 9/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294793 | 0.89 | NLRP3 (0.42) | NLRP3IL1BTNFKCNH2DRD2 | |
| SCHEMBL31681903 | 0.88 | NLRP3 (0.43) | NLRP3IL1BDRD2 | |
| SCHEMBL25256967 | 0.88 | NLRP3 (0.40) | NLRP3IL1BDRD2HTR2C | |
| SCHEMBL31681920 | 0.86 | NLRP3 (0.41) | NLRP3IL1BDRD2 | |
| SCHEMBL30488553 | 0.85 | NLRP3 (0.46) | NLRP3IL1B | |
| SCHEMBL29030512 | 0.85 | NLRP3 (0.46) | NLRP3IL1B | |
| SCHEMBL25859471 | 0.85 | NLRP3 (0.46) | NLRP3IL1B | |
| SCHEMBL30488591 | 0.85 | USP30 (0.37) | NLRP3 | |
| SCHEMBL29030471 | 0.85 | USP30 (0.37) | NLRP3 | |
| SCHEMBL29030472 | 0.85 | USP30 (0.37) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |