Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259280 | 0.88 | NLRP3 (0.40) | NLRP3DRD2HTR2CIL1B | |
| SCHEMBL29030515 | 0.83 | PIM1 (0.36) | NLRP3BTKPIK3CD | |
| SCHEMBL29030516 | 0.83 | PIM1 (0.36) | NLRP3BTKPIK3CD | |
| SCHEMBL30488567 | 0.83 | PIM1 (0.36) | NLRP3BTKPIK3CD | |
| SCHEMBL29030482 | 0.79 | NLRP3 (0.40) | NLRP3EHMT2BTKPIK3CD | |
| SCHEMBL29030480 | 0.79 | NLRP3 (0.40) | NLRP3EHMT2BTKPIK3CD | |
| SCHEMBL31197268 | 0.79 | EHMT2 (0.35) | NLRP3EHMT2 | |
| SCHEMBL25858451 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL25302366 | 0.77 | PIK3CD (0.41) | NLRP3EHMT2BTKPIK3CD | |
| SCHEMBL25302362 | 0.77 | PIK3CD (0.41) | NLRP3EHMT2BTKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |