SCHEMBL25259355

SCHEMBL25259355

C[Si](C)(C)CCOCn1ccnc1N1C[C@H](N)[C@@H](F)C1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25263633 0.81 KLKB1 (0.35) DGAT1
SCHEMBL25262520 0.77 USP30 (0.34) DGAT1
SCHEMBL26123856 0.71 MAP3K12 (0.34) —
SCHEMBL1488779 0.71 KMT2A (0.43) DGAT1
SCHEMBL1126106 0.70 TLR8 (0.47) DGAT1
SCHEMBL9638271 0.69 DGAT1 (0.41) DGAT1
SCHEMBL1793474 0.67 DGAT1 (0.38) DGAT1
SCHEMBL18675316 0.67 NISCH (0.39) DGAT1
Hydrochloric Acid SCHEMBL15455783 0.67 DGAT1 (0.37) DGAT1
SCHEMBL17810435 0.67 DGAT1 (0.37) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
EP-4463459-A1 STAT MODULATORS AND USES THEREOF Recludix Pharma, Inc. (US) 2024-11-20 — — EP disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 — — CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A DGAT1 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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