Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | IL1B | P01584 | 5/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25863027 | 1.00 | NLRP3 (0.36) | NLRP3IL1BTNF | |
| SCHEMBL30488519 | 1.00 | NLRP3 (0.36) | NLRP3IL1BTNF | |
| SCHEMBL25303313 | 0.85 | NLRP3 (0.36) | NLRP3IL1BTNF | |
| SCHEMBL25861117 | 0.85 | ALDH1A1 (0.36) | — | |
| SCHEMBL30488575 | 0.85 | PDE1B (0.33) | — | |
| SCHEMBL25294669 | 0.85 | PDE1B (0.33) | — | |
| SCHEMBL25294670 | 0.85 | PDE1B (0.33) | — | |
| SCHEMBL30488516 | 0.85 | PDE1B (0.33) | — | |
| SCHEMBL30488534 | 0.82 | NLRP3 (0.37) | NLRP3IL1BTNF | |
| SCHEMBL25258660 | 0.82 | NLRP3 (0.37) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |