Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.32 |
| ▸ | CDC25B | P30305 | 6/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20553048 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL20477154 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL28408184 | 0.90 | HTR1A (0.33) | BCHEPDE2AHTR1ATMPRSS2EGLN2 | |
| SCHEMBL29727834 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL17712276 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL27086511 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL12243178 | 0.90 | PDE2A (0.35) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL28404433 | 0.87 | PTPN1 (0.33) | BCHEPDE2AHTR1ATMPRSS2PTPN1 | |
| SCHEMBL15084421 | 0.87 | TMPRSS2 (0.39) | BCHEHTR1ATMPRSS2PTPN1CDC25B | |
| SCHEMBL28405132 | 0.86 | BCHE (0.38) | BCHEPDE2AHTR1APTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102472-A1 | ANTIVIRAL PRODRUGS AND FORMULATIONS THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-111233869-B | Novel compound for preparing Rudexilvir key intermediate and preparation method thereof | 杭州新博思生物医药有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-111233869-A | Novel compound for preparing Rudexilvir key intermediate and preparation method thereof | 杭州新博思生物医药有限公司 | 2020-06-05 | — | — | CN | disclosed |