Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.65 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.61 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14161697 | 0.91 | GRIN2B (0.76) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL12662876 | 0.84 | L3MBTL3 (0.73) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL13648726 | 0.83 | L3MBTL3 (0.72) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL13648728 | 0.83 | L3MBTL3 (0.72) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL28940844 | 0.83 | MBTD1 (0.55) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL20760190 | 0.82 | GRIN2B (0.65) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL372412 | 0.82 | GRIN2B (0.65) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL372411 | 0.82 | GRIN2B (0.65) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL737747 | 0.82 | GRIN2B (0.65) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL13240777 | 0.82 | GRIN2B (0.65) | GRIN2BMBTD1L3MBTL3L3MBTL1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695449-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190054198-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION | 2019-02-21 | — | — | US | disclosed |
| US-10098974-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-10-16 | — | — | US | disclosed |
| US-10058625-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2018-08-28 | — | — | US | disclosed |
| US-20150283273-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-10-08 | — | — | US | disclosed |
| US-20150283273-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-10-08 | — | — | US | disclosed |
| US-20150283273-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-10-08 | — | — | US | disclosed |
| US-20150132223-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-05-14 | — | — | US | disclosed |
| US-20150132223-A1 | Catalytic Radiofluorination | THE GENERAL HOSPITAL CORPORATION | 2015-05-14 | — | — | US | disclosed |
| US-9017724-B2 | Catalytic radiofluorination | THE GENERAL HOSPITAL CORPORATION (US) | 2015-04-28 | — | — | US | disclosed |
| US-7632485-B2 | Catalytic radiofluorination | MASSACHUSETTS GENERAL HOSPITAL (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632485-B2 | Catalytic radiofluorination | MASSACHUSETTS GENERAL HOSPITAL (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632485-B2 | Catalytic radiofluorination | MASSACHUSETTS GENERAL HOSPITAL (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1725269-A4 | CATALYTIC RADIOFLUORINATION | GEN HOSPITAL CORP (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008022319-A2 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008022319-A2 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |
| CN-1921893-A | Catalytic radiofluorination | GEN HOSPITAL CORP (US) | 2007-02-28 | — | — | CN | disclosed |
| EP-1725269-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2006-11-29 | — | — | EP | disclosed |
| US-20050260130-A1 | Arylphosphonium compounds containing fluorine-18 that are useful as imaging agents; in particular, the phosphonium compound is a tetraaryl phosphonium salt, [F-18]-(4-fluorophenyl)triphenylphosphonium nitrate; Position Emission Tomography | MASSACHUSETTS GENERAL HOSPITAL (US) | 2005-11-24 | — | — | US | disclosed |
| WO-2005082425-A1 | CATALYTIC RADIOFLUORINATION | THE GENERAL HOSPITAL CORPORATION (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10098974-B2 | Catalytic radiofluorination | ARSA, STS, KCNK18 | GRIN2B 4059/4885MBTD1 4765/4885L3MBTL3 2574/4885 |
| US-10058625-B2 | Catalytic radiofluorination | KCNJ5, KCNQ5, KCNK18 | GRIN2B 4487/4885MBTD1 4617/4885L3MBTL3 2704/4885 |
| US-20190054198-A1 | CATALYTIC RADIOFLUORINATION | KCNJ5, KCNQ5, KCNK18 | GRIN2B 4487/4885MBTD1 4617/4885L3MBTL3 2704/4885 |
| US-20050260130-A1 | Arylphosphonium compounds containing fluorine-18 that are useful as imaging agents; in particular, the phosphonium compound is a tetraaryl phosphonium salt, [F-18]-(4-fluorophenyl)triphenylphosphonium nitrate; Position Emission Tomography | KCNK18, KCNJ5, KCNQ5 | GRIN2B 3399/4885MBTD1 4521/4885L3MBTL3 1257/4885 |
| US-20150283273-A1 | Catalytic Radiofluorination | KCNJ5, KCNQ5, KCNK18 | GRIN2B 4487/4885MBTD1 4617/4885L3MBTL3 2704/4885 |
| US-10695449-B2 | Catalytic radiofluorination | KCNJ5, KCNQ5, KCNK18 | GRIN2B 4487/4885MBTD1 4617/4885L3MBTL3 2704/4885 |
| US-20150132223-A1 | Catalytic Radiofluorination | ARSA, KCNK18, STS | GRIN2B 3857/4885MBTD1 4691/4885L3MBTL3 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.