Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370930 | 0.86 | ATM (0.37) | SIGMAR1KDM4EALDH1A1CHRM5CHRM3 | |
| SCHEMBL25259016 | 0.79 | CTSK (0.47) | — | |
| SCHEMBL2916281 | 0.77 | SLC6A1 (0.47) | KDM4EALDH1A1SLC6A1GABRA5GABRB2 | |
| SCHEMBL1749205 | 0.76 | SSTR4 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL4202085 | 0.76 | SSTR4 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL1189936 | 0.76 | SSTR4 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL20501479 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL2013502 | 0.74 | SSTR4 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL14645713 | 0.73 | KDM4E (0.47) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL29372567 | 0.73 | KDM4E (0.47) | SIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137223-A1 | PAN-KRAS INHIBITORS AND USES THEREOF | NEWAVE PHARMACEUTICAL INC. (US) | 2023-07-20 | — | — | WO | disclosed |