SCHEMBL2526136

SCHEMBL2526136

C=CCCN(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.35
CA14 Q9ULX7 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
DGAT1 O75907 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24340294 0.89 HDAC6 (0.37) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL23620130 0.87 HDAC6 (0.34) HDAC6L3MBTL1CA14
SCHEMBL4149715 0.86 ALDH1A1 (0.42) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL30304345 0.86 ALDH1A1 (0.42) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL30304722 0.86 ALDH1A1 (0.42) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL15645124 0.85 CA14 (0.44) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL361154 0.83 HDAC6 (0.38) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL3752709 0.82 HDAC6 (0.40) HDAC6CA14HDAC1HDAC2DGAT1
SCHEMBL4683655 0.81 HDAC6 (0.37) HDAC6L3MBTL1CA14HDAC1HDAC2
SCHEMBL21424988 0.81 HDAC6 (0.37) HDAC6L3MBTL1CA14HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 US disclosed
EP-4584267-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
US-8524657-B2 Peptidic compounds UNIVERSITY OF WOLLONGONG (AU) 2013-09-03 US disclosed
US-8524657-B2 Peptidic compounds UNIVERSITY OF WOLLONGONG (AU) 2013-09-03 US disclosed
US-8524657-B2 Peptidic compounds UNIVERSITY OF WOLLONGONG (AU) 2013-09-03 US disclosed
EP-1836159-B1 Antibiotic binaphthyl derivatives UNIV WOLLONGONG (AU) 2013-04-10 EP disclosed
EP-1836159-B1 Antibiotic binaphthyl derivatives UNIV WOLLONGONG (AU) 2013-04-10 EP disclosed
US-20110312875-A1 PEPTIDIC COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2011-12-22 US disclosed
US-20110312875-A1 PEPTIDIC COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2011-12-22 US disclosed
US-8039430-B2 Peptidic compounds UNIVERSITY OF WOLLONGONG (AU) 2011-10-18 US disclosed
US-8039430-B2 Peptidic compounds UNIVERSITY OF WOLLONGONG (AU) 2011-10-18 US disclosed
EP-2199300-A2 Peptidic compounds The University Of Wollongong (AU) 2010-06-23 EP disclosed
EP-2199300-A2 Peptidic compounds The University Of Wollongong (AU) 2010-06-23 EP disclosed
EP-1836159-A4 PEPTIDIC COMPOUNDS UNIV WOLLONGONG (AU) 2009-02-25 EP disclosed
US-20080300287-A1 Peptidic Compounds UNIVERSITY OF WOLLONGONG (AU) 2008-12-04 US disclosed
US-20080300287-A1 Peptidic Compounds UNIVERSITY OF WOLLONGONG (AU) 2008-12-04 US disclosed
US-20080300287-A1 Peptidic Compounds UNIVERSITY OF WOLLONGONG (AU) 2008-12-04 US disclosed
EP-1836159-A1 PEPTIDIC COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2007-09-26 EP disclosed
WO-2006074501-A1 PEPTIDIC COMPOUNDS UNIVERSITY OF WOLLONGONG (AU) 2006-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300287-A1 Peptidic Compounds VIP, NGLY1, FURIN HDAC6 512/4885L3MBTL1 3820/4885CA14 2294/4885
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 HDAC6 1199/4885L3MBTL1 853/4885CA14 1886/4885
US-20110312875-A1 PEPTIDIC COMPOUNDS VIP, NGLY1, FURIN HDAC6 445/4885L3MBTL1 3778/4885CA14 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.