Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 5/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.44 |
| ▸ | ATR | Q13535 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25304235 | 0.91 | CYP4F2 (0.43) | CYP4F2CYP4A11ATRKDM4EMEN1 | |
| SCHEMBL24693881 | 0.75 | CYP4F2 (0.50) | CYP4F2CYP4A11ATRKMT2A | |
| SCHEMBL17112012 | 0.74 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| SCHEMBL23535790 | 0.73 | CYP4F2 (0.50) | CYP4F2CYP4A11ATR | |
| SCHEMBL4079169 | 0.72 | KDM4E (0.44) | KDM4E | |
| SCHEMBL15016182 | 0.72 | CYP4F2 (0.50) | CYP4F2CYP4A11ATR | |
| SCHEMBL19881080 | 0.71 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| Potassium Ion SCHEMBL5819229 | 0.71 | KDM4E (0.43) | KDM4E | |
| SCHEMBL5819232 | 0.71 | KDM4E (0.43) | KDM4E | |
| SCHEMBL19276681 | 0.71 | CYP4F2 (0.65) | CYP4F2CYP4A11ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |