SCHEMBL25262181

SCHEMBL25262181

CC(C)COC(=O)c1c(C(=O)O)c(C(=O)OC(=O)c2c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c2C(=O)O)c(C(=O)OC(=O)c2c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c2C(=O)O)c(C(=O)OCC(C)C)c1C(=O)OCC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
TSHR P16473 4/20 0.47
MAPT P10636 3/20 0.38
CACNA1F O60840 1/20 0.35
CACNA1D Q01668 1/20 0.35
CACNA1S Q13698 1/20 0.35
CACNA1C Q13936 1/20 0.35
PLA2G1B P04054 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
JMJD6 Q6NYC1 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
CHRM2 P08172 2/20 0.33
CHRM4 P08173 2/20 0.33
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28744988 1.00 ALDH1A1 (0.47) ALDH1A1TSHRMAPTCACNA1FCACNA1D
SCHEMBL27557396 1.00 ALDH1A1 (0.47) ALDH1A1TSHRMAPTCACNA1FCACNA1D
SCHEMBL28253923 0.81 PKM (0.43) ALDH1A1SMN1; SMN2KDM4ETDP1TP53
SCHEMBL28169153 0.81 PKM (0.43) ALDH1A1SMN1; SMN2KDM4ETDP1TP53
SCHEMBL28365859 0.80 TSHR (0.44) ALDH1A1TSHRMAPTKDM4EHSD17B10
SCHEMBL28149046 0.78 KDM4E (0.37) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL27523171 0.78 KDM4E (0.37) ALDH1A1KDM4EMEN1KMT2ALMNA
SCHEMBL27562004 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL27534697 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL27702993 0.78 ALDH1A1 (0.50) ALDH1A1TSHRMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3747860-B1 NOVEL CYCLOHEXANONE BASED PLASTICISERS BASF SE (DE) 2023-07-26 EP disclosed