Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 9/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.55 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29381812 | 1.00 | CYP2A6 (1.00) | CYP2A6PDPK1CYP3A4CYP2C9CYP2B6 | |
| Acetic Acid SCHEMBL5455986 | 0.88 | CYP2A6 (0.78) | CYP2A6PDPK1CYP3A4CYP2C9CYP2B6 | |
| Acetic Acid Methyl Ester SCHEMBL5465492 | 0.84 | CYP2A6 (0.71) | CYP2A6PDPK1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL1772043 | 0.83 | CYP2A6 (0.70) | CYP2A6PDPK1CYP3A4CYP2C9CYP2B6 | |
| Ethoxycarbonyl Group SCHEMBL28053332 | 0.82 | CYP2A6 (0.68) | CYP2A6PDPK1CYP3A4CYP2C9CYP2B6 | |
| 2-Phenylthiazole SCHEMBL70646 | 0.79 | PDPK1 (1.00) | CYP2A6PDPK1CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL7079127 | 0.78 | PDPK1 (0.67) | CYP2A6PDPK1MKNK1MKNK2RAB9A | |
| 2-Phenylthiazole SCHEMBL4939218 | 0.77 | PDPK1 (0.95) | CYP2A6PDPK1CYP3A4CYP2C9ALDH1A1 | |
| 2-Phenylthiazole SCHEMBL10519953 | 0.77 | PDPK1 (0.95) | CYP2A6PDPK1KDM4ERAB9ALOXL2 | |
| 2-Phenylthiazole SCHEMBL10667585 | 0.77 | PDPK1 (0.95) | CYP2A6PDPK1CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060043-B1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | CORTEVA AGRISCIENCE LLC (US) | 2025-11-26 | — | — | EP | claimed |
| CN-110407839-A | The preparation and application of the triazol heterocycle compound of the structure containing heteroaryl amide | UNIV JIANGXI NORMAL SCI & TECH | 2019-11-05 | — | — | CN | claimed |
| US-9445597-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-09-20 | — | — | US | claimed |
| EP-3060043-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences, LLC (US) | 2016-08-31 | — | — | EP | claimed |
| EP-3055301-A1 | RHO KINASE INHIBITORS | Kadmon Corporation, LLC (US) | 2016-08-17 | — | — | EP | claimed |
| CN-105658059-A | Pesticidal compositions and related methods | 美国陶氏益农公司 | 2016-06-08 | — | — | CN | claimed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | claimed |
| CN-104640442-A | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE | 2015-05-20 | — | — | CN | claimed |
| WO-2015061155-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | claimed |
| EP-2863738-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2015-04-29 | — | — | EP | claimed |
| WO-2013186089-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2013-12-19 | — | — | WO | claimed |
| WO-2013010947-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2013-01-24 | — | — | WO | claimed |
| WO-2013010946-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS I | BASF SE (DE) | 2013-01-24 | — | — | WO | claimed |
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2008-08-07 | — | — | US | claimed |
| WO-2005066162-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2005-07-21 | — | — | WO | claimed |
| US-5866583-A | Substituted 2,4-diaminopyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | claimed |
| EP-0680967-B1 | Erythromycin derivatives, their process of preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (FR) | 1998-10-14 | — | — | EP | claimed |
| US-5470862-A | Intravenous anesthetics | OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) | 1995-11-28 | — | — | US | claimed |
| WO-1995029929-A1 | NOVEL ERYTHROMYCIN DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS | ROUSSEL UCLAF (FR) | 1995-11-09 | — | — | WO | claimed |
| EP-0680967-A1 | Erythromycin derivatives, their process of preparation and their use as medicaments | ROUSSEL-UCLAF (FR) | 1995-11-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | CYP2A13, CYP2A6, CYP2B6 | CYP2A6 2/4885PDPK1 2660/4885CYP3A4 45/4885 |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | PTMS, PDXK, TH | CYP2A6 1875/4885PDPK1 653/4885CYP3A4 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.