Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 3/20 | 0.69 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.69 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.69 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.69 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.69 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.69 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 13/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | FRK | P42685 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218871 | 0.87 | CSNK1D (0.68) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL15022099 | 0.86 | CSNK1D (0.58) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL3272515 | 0.86 | BRAF (0.61) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL25263176 | 0.84 | MAPK13 (0.66) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL5259262 | 0.83 | CSNK1D (0.69) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL15022104 | 0.83 | MAPK13 (0.54) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL5698604 | 0.82 | CSNK1D (1.00) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL5257540 | 0.82 | CSNK1D (1.00) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL25220251 | 0.81 | CSNK1D (0.75) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 | |
| SCHEMBL15022103 | 0.80 | MAPK13 (0.51) | CSNK1DCSNK1EMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| EP-4126878-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |
| CN-115298183-A | Compounds as casein kinase inhibitors | 北京原基华毅生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | CSNK2A3, CSNK1A1, CSNK1G3 | CSNK1D 10/4885CSNK1E 9/4885MAPK13 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.