Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533303 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL2523653 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL21623743 | 0.93 | KDM4C (0.44) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL2533371 | 0.93 | CA1 (0.41) | CA1KDM4EKDM4CKDM4APHF8 | |
| SCHEMBL2529668 | 0.91 | CA1 (0.44) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL2529894 | 0.89 | KDM4E (0.47) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL2532066 | 0.89 | KDM4E (0.47) | GPR84FFAR1FFAR4CA1KDM4E | |
| SCHEMBL2531343 | 0.88 | CA1 (0.41) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL5613242 | 0.88 | CA1 (0.48) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL4575366 | 0.85 | KDM4C (0.47) | FFAR1FFAR4CA1KDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |