Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629586 | 0.87 | ACE (0.47) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL629585 | 0.87 | ACE (0.47) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL25175295 | 0.87 | ACE (0.47) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL67044 | 0.85 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL27877016 | 0.85 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL6219872 | 0.85 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL67045 | 0.85 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL85536 | 0.85 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL20492528 | 0.84 | HSD17B10 (0.68) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| Ammonia Solution, Strong SCHEMBL28264574 | 0.84 | HSD17B10 (0.68) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088804-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2338878-A2 | N-hydroxyamide derivatives possessing antibacterial activity | Vicuron Pharmaceuticals, Inc. (US) | 2011-06-29 | — | — | EP | disclosed |