SCHEMBL67045

SCHEMBL67045

CC(C)(C)OC(=O)N1CCCC1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.60
RAB9A P51151 1/20 0.56
LMNA P02545 2/20 0.54
CYP2C19 P33261 1/20 0.54
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 2/20 0.53
NPSR1 Q6W5P4 1/20 0.51
UCHL1 P09936 2/20 0.49
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85536 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL67044 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL27877016 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL6219872 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL20492528 0.98 HSD17B10 (0.68) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
Ammonia Solution, Strong SCHEMBL28264574 0.98 HSD17B10 (0.68) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
Hydrazine SCHEMBL28122430 0.97 HSD17B10 (0.66) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL1809663 0.95 HSD17B10 (0.64) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL77858 0.95 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL65491 0.95 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2308 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036817-A C-alkyl carbon glycoside and preparation method thereof 江西师范大学 2026-05-15 CN claimed
CN-118702926-A Preparation method of MOF@Pro HNs hollow mesoporous network nanomaterial, product and application thereof 重庆邮电大学 2024-09-27 CN claimed
CN-117682974-B Preparation method of 2-propionyl-1-pyrroline 济南悟通生物科技有限公司 2024-04-16 CN claimed
CN-113185439-B V-shaped chiral carboxylic acid ligand, preparation method and application thereof 合肥工业大学 2024-03-12 CN claimed
CN-117682974-A Preparation method of 2-propionyl-1-pyrroline 济南悟通生物科技有限公司 2024-03-12 CN claimed
CN-117658830-A Preparation method of trans-2-aminocyclopentanol with high optical purity 大连双硼医药化工有限公司 2024-03-08 CN claimed
CN-117362271-A Method for preparing nicotine 湖北和诺生物工程股份有限公司 2024-01-09 CN claimed
WO-2024000877-A1 PREPARATION METHOD FOR NICOTINE 湖北和诺生物工程股份有限公司 2024-01-04 WO claimed
CN-110240631-B Chiral isoindolone cyclopeptide derivative, preparation method and application thereof 哈尔滨师范大学 2023-02-17 CN claimed
US-11168084-B2 Purine based compounds as toll-like receptor 9 antagonist COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2021-11-09 US claimed
EP-3707140-B1 PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONISTS COUNCIL SCIENT IND RES (IN) 2021-10-13 EP claimed
CN-109134336-B Diaryl ether compound, preparation method and application thereof 北京大学深圳研究生院 2021-08-03 CN claimed
US-20200347062-A1 PURINE BASED COMPOUNDS AS TOLL-LIKE RECEPTOR 9 ANTAGONIST COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2020-11-05 US claimed
EP-1867649-B1 PIPERIDYL-2, 6-DIONE DERIVATIVES USED TO INHIBIT CELLS FROM RELEASING TUMOR NECROSIS FACTOR TIAN JIN HEMAY BIO TECH CO LTD (CN) 2012-12-12 EP claimed
EP-1581525-A2 COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS AstraZeneca AB (SE) 2005-10-05 EP claimed
US-20040106607-A1 New compounds ASTRAZENECA AB AND NPS PHARMACEUTICALS, INC. 2004-06-03 US claimed
WO-2004014902-A2 COMPOUNDS HAVING AN ACTIVITY AT METABOTROPIC GLUTAMATE RECEPTORS ASTRAZENECA AB (SE) 2004-02-19 WO claimed
EP-0155809-B1 RENIN INHIBITORS CONTAINING STATINE OR DERIVATIVES THEREOF PFIZER INC. (US) 1990-05-09 EP claimed
US-4749687-A Renin inhibitors containing statine or derivatives thereof PFIZER INC. (US) 1988-06-07 US claimed
EP-0155809-A2 Renin inhibitors containing statine or derivatives thereof PFIZER INC. (US) 1985-09-25 EP claimed