SCHEMBL67044

SCHEMBL67044

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.60
RAB9A P51151 1/20 0.56
LMNA P02545 2/20 0.54
CYP2C19 P33261 1/20 0.54
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 2/20 0.53
NPSR1 Q6W5P4 1/20 0.51
UCHL1 P09936 2/20 0.49
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL85536 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL27877016 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL67045 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL6219872 1.00 HSD17B10 (0.69) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL20492528 0.98 HSD17B10 (0.68) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
Ammonia Solution, Strong SCHEMBL28264574 0.98 HSD17B10 (0.68) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
Hydrazine SCHEMBL28122430 0.97 HSD17B10 (0.66) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL1809663 0.95 HSD17B10 (0.64) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL77858 0.95 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19
SCHEMBL65491 0.95 HSD17B10 (0.63) HSD17B10SMN1; SMN2RAB9ALMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4511 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071449-A Substituted biphenyl compounds and application thereof in synthesis of cola pyrroside 北京凯因格领生物技术有限公司 2026-05-22 CN claimed
CN-122059934-A PD-L1 protein degradation targeting chimeric and preparation method and application thereof 首都医科大学 2026-05-19 CN claimed
CN-122037174-A Preparation method of polyethylene glycol monomethyl ether-polyproline block copolymer rich in PPII 电子科技大学 2026-05-15 CN claimed
CN-122036817-A C-alkyl carbon glycoside and preparation method thereof 江西师范大学 2026-05-15 CN claimed
CN-122011119-A Preparation method and application of bionic collagen cyclohexapeptide 成都欣肽生物科技有限公司 2026-05-12 CN claimed
CN-122010833-A Method for catalyzing tension ring heteroaryl by iron 南京师范大学 2026-05-12 CN claimed
CN-115873034-B Semi-active phosphoramide ligand and preparation method thereof 上海毕臣生化科技有限公司 2025-06-24 CN claimed
CN-119798139-A Method for synthesizing phenolic compound by iron-catalyzed hydroxylation reaction of aromatic compound 南京师范大学 2025-04-11 CN claimed
CN-119798083-A Iron-catalyzed aromatic compound carbon-hydrogen bond hydroxylation nitration method 南京师范大学 2025-04-11 CN claimed
CN-119798062-A Method for catalyzing quinone hydroxylation reaction of alkene by iron 南京师范大学 2025-04-11 CN claimed
US-7049440-B2 Chemical intermediate for tricyclic compound SCHERING CORPORATION (US) 2006-05-23 US claimed
US-6951946-B2 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. (US) 2005-10-04 US claimed
EP-1556358-A2 ENANTIOSELECTIVE ALKYLATION OF TRICYCLIC COMPOUNDS SCHERING CORPORATION (US) 2005-07-27 EP claimed
US-20050154211-A1 Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates KOLB HARTMUTH C (US) 2005-07-14 US claimed
US-20040122232-A1 Enantioselective process SCHERING CORPORATION 2004-06-24 US claimed
WO-2004031153-A2 ENANTIOSELECTIVE ALKYLATION OF TRICYCLIC COMPOUNDS SCHERING CORPORATION (US) 2004-04-15 WO claimed
US-20040019215-A1 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. 2004-01-29 US claimed
EP-0155809-B1 RENIN INHIBITORS CONTAINING STATINE OR DERIVATIVES THEREOF PFIZER INC. (US) 1990-05-09 EP claimed
US-4749687-A Renin inhibitors containing statine or derivatives thereof PFIZER INC. (US) 1988-06-07 US claimed
EP-0155809-A2 Renin inhibitors containing statine or derivatives thereof PFIZER INC. (US) 1985-09-25 EP claimed