Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25225351 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL1751135 | 0.74 | PRKDC (0.33) | PDE2A | |
| SCHEMBL25278327 | 0.74 | PRKDC (0.33) | PDE2A | |
| SCHEMBL25270724 | 0.74 | PRKDC (0.33) | PDE2A | |
| SCHEMBL24457882 | 0.73 | KDM4E (0.39) | — | |
| SCHEMBL20303786 | 0.72 | KMT2A (0.44) | PDE2AMEN1KMT2A | |
| SCHEMBL20855517 | 0.72 | PDE10A (0.39) | PDE2APDE4BMEN1KMT2A | |
| SCHEMBL17808315 | 0.70 | ALDH1A1 (0.32) | — | |
| SCHEMBL20091003 | 0.70 | IRAK4 (0.33) | PDE2A | |
| SCHEMBL1751970 | 0.67 | SQOR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |