SCHEMBL2527896

SCHEMBL2527896

O=S(=O)(O)c1ccc(Cl)c2ccoc12

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
FABP4 P15090 1/20 0.33
TTR P02766 1/20 0.31
COMT P21964 1/20 0.30
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17843510 0.75 CYP1A2 (0.39)
SCHEMBL23084790 0.73 MEN1 (0.34) POLBTTRCOMTAURKAAURKB
SCHEMBL28286971 0.73 TET2 (0.42) TTRCOMTAURKAAURKB
SCHEMBL23087388 0.72 CYP3A4 (0.39)
Ammonia Solution, Strong SCHEMBL28809072 0.71 TET2 (0.41) TTRCOMTAURKAAURKB
Ammonia Solution, Strong SCHEMBL29694481 0.71 TET2 (0.41) TTRCOMTAURKAAURKB
SCHEMBL3182766 0.71 CYP1A2 (0.54) POLBFABP4TTRCOMTAURKA
SCHEMBL28878040 0.70 KMT2A (0.38) POLB
SCHEMBL25403991 0.70 ALDH1A1 (0.41) POLB
SCHEMBL31347699 0.70 ALDH1A1 (0.41) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050250170-A1 Determination of metal ions in solution by photoluminescence anisotropy THOMPSON, RICHARD B. 2005-11-10 US claimed
US-20020055091-A1 Determination of metal ions in solution by photoluminescence anisotropy UNIVERSITY OF PENNSYLVANIA 2002-05-09 US claimed
US-6284544-B1 MIXING AQUEOUS SOLUTION WITH A PHOTOLUMINESCENT LABELED MACROMOLECULE THAT CAN REVERSIBLY BIND ION FORMING A COMPLEX, IRRADIATING SOLUTION WITH POLARIZED LIGHT TO BE ABSORBED BY THE LUMINESCENT, RESOLVING THE EMISSION/CALCULATE ANISOTROPHY UNIVERSITY OF PENNSYLVANIA 2001-09-04 US claimed
US-8038947-B2 Analyte sensor devices and holders, and methods and systems utilizing the same UNIVERSITY OF MARYLAND, BALTIMORE (US) 2011-10-18 US disclosed
US-7842491-B2 Determination of metal ions in solution by photoluminescence anisotropy Thompson, Richard B. (US) 2010-11-30 US disclosed
US-20090042311-A1 ANALYTE SENSOR DEVICES AND HOLDERS, AND METHODS AND SYSTEMS UTILIZING THE SAME NATIONAL SCIENCE FOUNDATION 2009-02-12 US disclosed
US-20050250170-A1 Determination of metal ions in solution by photoluminescence anisotropy THOMPSON, RICHARD B. 2005-11-10 US disclosed
US-20020055091-A1 Determination of metal ions in solution by photoluminescence anisotropy UNIVERSITY OF PENNSYLVANIA 2002-05-09 US disclosed
US-6284544-B1 MIXING AQUEOUS SOLUTION WITH A PHOTOLUMINESCENT LABELED MACROMOLECULE THAT CAN REVERSIBLY BIND ION FORMING A COMPLEX, IRRADIATING SOLUTION WITH POLARIZED LIGHT TO BE ABSORBED BY THE LUMINESCENT, RESOLVING THE EMISSION/CALCULATE ANISOTROPHY UNIVERSITY OF PENNSYLVANIA 2001-09-04 US disclosed
US-6197258-B1 DETECTOR FOR DETERMINING AQUEOUS METAL ION CONCENTRATION INCLUDING A PHOTOLUMINESCENT LABEL BOUND TO AN ANALYTE BINDING MACROMOLECULE OF HUMAN APOCARBONIC ANHYDRASE OR DERIVATIVE UNIVERSITY OF MARYLAND, BALTIMORE 2001-03-06 US disclosed