Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528179 | 0.93 | CES2 (0.39) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL2530964 | 0.91 | CES2 (0.42) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL2532284 | 0.85 | — | — | |
| SCHEMBL106298 | 0.83 | CES2 (0.48) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL19973390 | 0.83 | CES2 (0.48) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL2529000 | 0.82 | CA1 (0.38) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL3409269 | 0.81 | CES2 (0.56) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL2528149 | 0.81 | CAMK2A (0.40) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL2530545 | 0.80 | CA1 (0.45) | CES2LTA4HMEN1FAAHMAPK1 | |
| SCHEMBL21318254 | 0.79 | CES2 (0.59) | CES2MEN1FAAHMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |