Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516233 | 0.98 | EPHX1 (0.48) | EPHX1NAAAHCAR2S1PR2S1PR1 | |
| SCHEMBL28816929 | 0.98 | EPHX1 (0.48) | EPHX1NAAAHCAR2S1PR2S1PR1 | |
| SCHEMBL9490477 | 0.98 | EPHX1 (0.48) | EPHX1NAAAHCAR2S1PR2S1PR1 | |
| SCHEMBL1495274 | 0.93 | — | — | |
| SCHEMBL27797987 | 0.83 | — | — | |
| SCHEMBL4650512 | 0.82 | CES2 (0.47) | EPHX1NAAAS1PR2S1PR1S1PR3 | |
| SCHEMBL1756788 | 0.82 | EPHX1 (0.45) | EPHX1NAAAS1PR2S1PR1S1PR3 | |
| SCHEMBL11001295 | 0.81 | TSHR (0.45) | EPHX1HCAR2CES2ALOX15TSHR | |
| SCHEMBL21724593 | 0.80 | EPHX1 (0.48) | EPHX1NAAACES2CNR2TRPV1 | |
| SCHEMBL4762004 | 0.80 | CES2 (0.50) | EPHX1NAAACES2CNR2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | claimed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | claimed |
| CN-110878034-A | Method for preparing amine compound by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-03-13 | — | — | CN | claimed |
| CN-110283103-A | A kind of decarboxylation amination of base catalysis prepares amino-acid ester/amide method | 北京理工大学 | 2019-09-27 | — | — | CN | claimed |
| CN-102216257-A | GABA conjugates and methods of use thereof | KYPHIA PHARMACEUTICALS INC | 2011-10-12 | — | — | CN | claimed |
| CN-101898977-A | GABA (Gamma-Aminobutyric Acid) conjugates and using method thereof | FENG XU | 2010-12-01 | — | — | CN | claimed |
| CN-101679897-A | Method of lubricating-an aluminium silicate composite surface with a lubricant comprising ashless, sulphur, phosphorus free antiwear agent | LUBRIZOL CORP | 2010-03-24 | — | — | CN | claimed |
| CN-101291916-A | 9-aminocarbonyl substituted derivatives of glycylcyclines | WYETH CORP (US) | 2008-10-22 | — | — | CN | claimed |
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | disclosed |
| CN-110878034-A | Method for preparing amine compound by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-03-13 | — | — | CN | disclosed |
| CN-110283103-A | A kind of decarboxylation amination of base catalysis prepares amino-acid ester/amide method | 北京理工大学 | 2019-09-27 | — | — | CN | disclosed |
| CN-101291916-A | 9-aminocarbonyl substituted derivatives of glycylcyclines | WYETH CORP (US) | 2008-10-22 | — | — | CN | disclosed |
| EP-1919879-A1 | 9-AMINOCARBONYLSUBSTITUTED DERIVATIVES OF GLYCYLCYCLINES | Wyeth a Corporation of the State of Delaware (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007027599-A1 | 9-AMINOCARBONYLSUBSTITUTED DERIVATIVES OF GLYCYLCYCLINES | WYETH (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | WYETH (US) | 2007-03-01 | — | — | US | disclosed |
| EP-0073146-A1 | Method and material for the formation of silver halide color photographic image | KONICA CORPORATION (JP) | 1983-03-02 | — | — | EP | disclosed |
| US-4160077-A | Process of crosslinking unsaturated hydrocarbon polymers employing novel carbamates | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049564-A1 | 9-Aminocarbonylsubstituted derivatives of glycylcyclines | Q6ZSR9, GMPS, RPS10 | EPHX1 4541/4885NAAA 833/4885HCAR2 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.