SCHEMBL8516233

SCHEMBL8516233

CCCCCCCONC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
NAAA Q02083 1/20 0.47
CES2 O00748 1/20 0.45
S1PR2 O95136 1/20 0.44
S1PR1 P21453 1/20 0.44
S1PR3 Q99500 1/20 0.44
EPHX2 P34913 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
CNR2 P34972 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
GPR84 Q9NQS5 7/20 0.43
PPARG P37231 6/20 0.43
PPARD Q03181 6/20 0.43
PPARA Q07869 6/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490477 1.00 EPHX1 (0.48) EPHX1NAAACES2S1PR2S1PR1
SCHEMBL28816929 1.00 EPHX1 (0.48) EPHX1NAAACES2S1PR2S1PR1
SCHEMBL252825 0.98 EPHX1 (0.45) EPHX1NAAACES2S1PR2S1PR1
SCHEMBL1495274 0.91
SCHEMBL18525732 0.83 CES2 (0.50) EPHX1NAAACES2CNR2TRPV1
SCHEMBL4762004 0.83 CES2 (0.50) EPHX1NAAACES2CNR2TRPV1
SCHEMBL29818646 0.83 EPHX1 (0.48) EPHX1NAAACES2CNR2TRPV1
SCHEMBL11670372 0.83 EPHX1 (0.48) EPHX1NAAACES2CNR2TRPV1
SCHEMBL21724593 0.83 EPHX1 (0.48) EPHX1NAAACES2CNR2TRPV1
SCHEMBL3267106 0.83 EPHX1 (0.48) EPHX1NAAACES2CNR2TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11116543-A None JP disclosed
JP-H11116543-A PRODUCTION OF OPTICALLY ACTIVE 1-ARYLETHOXYAMINE DERIVATIVE AND INTERMEDIATE OF THE SAME MITSUBISHI CHEMICAL CORP 1999-04-27 JP disclosed