Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
| ▸ | WNT3A | P56704 | 4/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254330 | 0.86 | HDAC1 (0.47) | CHRM4WNT3AMAPK1 | |
| SCHEMBL246113 | 0.86 | WNT3A (0.57) | WNT3A | |
| SCHEMBL252827 | 0.84 | WNT3A (0.50) | WNT3ASLC2A1 | |
| SCHEMBL10257461 | 0.84 | HDAC2 (0.44) | WNT3ASLC2A1 | |
| SCHEMBL10256705 | 0.82 | WNT3A (0.48) | WNT3A | |
| SCHEMBL245851 | 0.79 | WNT3A (0.56) | WNT3A | |
| SCHEMBL248216 | 0.76 | WNT3A (0.69) | WNT3A | |
| SCHEMBL246614 | 0.74 | WNT3A (0.53) | WNT3A | |
| SCHEMBL248940 | 0.72 | WNT3A (0.48) | WNT3AMAPK1 | |
| SCHEMBL254331 | 0.71 | HPGD (0.42) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588453-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003189-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2012-01-05 | — | — | WO | disclosed |