Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | WNT3A | P56704 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252826 | 0.86 | CHRM4 (0.48) | WNT3AMAPK1CHRM4 | |
| SCHEMBL248940 | 0.85 | WNT3A (0.48) | WNT3AKDM4EALDH1A1MAPK1RAB9A | |
| SCHEMBL254331 | 0.84 | HPGD (0.42) | HDAC1WNT3ASMN1; SMN2 | |
| SCHEMBL1912418 | 0.83 | HPGDS (0.45) | HDAC1HDAC2HDAC3 | |
| SCHEMBL14817880 | 0.82 | TBK1 (0.47) | HDAC1WNT3ASMN1; SMN2 | |
| SCHEMBL246113 | 0.71 | WNT3A (0.57) | WNT3A | |
| SCHEMBL252827 | 0.70 | WNT3A (0.50) | WNT3A | |
| SCHEMBL10257461 | 0.69 | HDAC2 (0.44) | HDAC1WNT3AHDAC2HDAC3 | |
| SCHEMBL10256705 | 0.69 | WNT3A (0.48) | WNT3ASMN1; SMN2 | |
| SCHEMBL247860 | 0.68 | WNT3A (0.55) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588453-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003189-A1 | COMPOSITIONS AND METHODS FOR MODULATING THE WNT SIGNALING PATHWAY | IRM LLC (BM) | 2012-01-05 | — | — | WO | disclosed |