Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25292442 | 0.83 | TTK (0.41) | TTK | |
| SCHEMBL25241788 | 0.81 | TYK2 (0.39) | PIK3C3 | |
| SCHEMBL25289334 | 0.81 | MAPT (0.31) | PIK3C3TTK | |
| SCHEMBL25287069 | 0.80 | BACE1 (0.37) | PIK3C3 | |
| SCHEMBL25242170 | 0.79 | TYK2 (0.39) | PIK3C3 | |
| SCHEMBL25244416 | 0.78 | TYK2 (0.39) | PIK3C3 | |
| SCHEMBL25240241 | 0.77 | TYK2 (0.34) | PIK3C3 | |
| SCHEMBL25285749 | 0.75 | TYK2 (0.36) | TTK | |
| SCHEMBL25283616 | 0.74 | PIK3C3 (0.34) | PIK3C3 | |
| SCHEMBL25286881 | 0.72 | TTK (0.57) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |