Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25241788 | 0.87 | TYK2 (0.39) | PIK3C3TYK2 | |
| SCHEMBL25242170 | 0.85 | TYK2 (0.39) | PIK3CAPIK3C3TYK2 | |
| SCHEMBL25244416 | 0.84 | TYK2 (0.39) | PIK3C3TYK2 | |
| SCHEMBL25240241 | 0.82 | TYK2 (0.34) | PIK3CAPIK3C3TYK2 | |
| SCHEMBL25289334 | 0.81 | MAPT (0.31) | PIK3C3TYK2 | |
| SCHEMBL25292442 | 0.81 | TTK (0.41) | TYK2 | |
| SCHEMBL25283690 | 0.80 | PIK3C3 (0.31) | PIK3C3 | |
| SCHEMBL25283616 | 0.80 | PIK3C3 (0.34) | PIK3C3TYK2 | |
| SCHEMBL25241375 | 0.79 | TYK2 (0.49) | TYK2 | |
| SCHEMBL25241283 | 0.76 | PIK3C3 (0.34) | PIK3CAPIK3C3TYK2MTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |