SCHEMBL252843

SCHEMBL252843

C=CCC(C)(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.42
GLRB P48167 1/20 0.42
GABBR2 O75899 2/20 0.42
GABBR1 Q9UBS5 2/20 0.42
GAA P10253 4/20 0.42
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
USP2 O75604 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
BLM P54132 1/20 0.41
ATM Q13315 1/20 0.41
HIF1A Q16665 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GPR55 Q9Y2T6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706529 0.80 LMNA (0.47) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL11268974 0.79 GLRA3 (0.43) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL5373171 0.78 ALDH1A1 (0.41) ALDH1A1TSHRMAPTLMNAHTT
SCHEMBL5373177 0.78 ALDH1A1 (0.41) ALDH1A1TSHRMAPTLMNAHTT
SCHEMBL207155 0.78 LMNA (0.45) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL11019109 0.78 GLRA3 (0.44) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL4138805 0.78 GLRA3 (0.44) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL17912258 0.76 ALDH1A1 (0.53) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL7174365 0.76 ALDH1A1 (0.37) GLRA3GLRBGABBR2GABBR1GAA
SCHEMBL11240007 0.76 GLRA3 (0.46) GLRA3GLRBGABBR2GABBR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486097-B1 CROSSLINKABLE COMPOSITIONS WACKER CHEMIE AG (DE) 2013-07-24 EP disclosed
US-8399575-B2 Crosslinkable materials based on organosilicon compounds WACKER CHEMIE AG (DE) 2013-03-19 US disclosed
US-20120004364-A1 Crosslinkable Materials Based On Organosilicon Compounds WACKER CHEMIE AG (DE) 2012-01-05 US disclosed
EP-2031024-B1 Crosslinkable materials based on organosilicon compounds WACKER CHEMIE AG (DE) 2010-02-24 EP disclosed
EP-2150577-A1 CROSS-LINKABLE MASSES COMPRISING PHOSPHORUS COMPOUNDS Wacker Chemie AG (DE) 2010-02-10 EP disclosed
US-20090062471-A1 CROSSLINKABLE MATERIALS BASED ON ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-05 US disclosed
EP-2031024-A1 Crosslinkable materials based on organosilicon compounds Wacker Chemie AG (DE) 2009-03-04 EP disclosed
WO-2008141951-A1 CROSS-LINKABLE MASSES COMPRISING PHOSPHORUS COMPOUNDS WACKER CHEMIE AG (DE) 2008-11-27 WO disclosed