Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285401 | 1.00 | VNN1 (0.49) | VNN1CYP3A4CYP2C9CYP2C19EPHX2 | |
| SCHEMBL28124690 | 0.69 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP2C19EPHX2NR1H4 | |
| SCHEMBL23365839 | 0.68 | SOAT1 (0.40) | EPHX2SOAT1 | |
| SCHEMBL25285515 | 0.67 | SOAT1 (0.42) | SOAT1 | |
| SCHEMBL25285516 | 0.67 | SOAT1 (0.42) | SOAT1 | |
| SCHEMBL23365842 | 0.67 | SOAT1 (0.40) | SOAT1 | |
| SCHEMBL25282093 | 0.66 | VNN1 (1.00) | VNN1EPHX2LTA4HNR1H4GCGR | |
| SCHEMBL25282094 | 0.66 | VNN1 (1.00) | VNN1EPHX2LTA4HNR1H4GCGR | |
| SCHEMBL23365821 | 0.66 | SOAT1 (0.41) | SOAT1 | |
| SCHEMBL2251955 | 0.64 | VNN1 (0.51) | VNN1EPHX2LTA4HNR1H4CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12128016-B2 | Vanin-1 inhibitor | EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIVERSITY (JP) | 2024-10-29 | — | — | US | disclosed |
| US-20240277639-A1 | VANIN-1 INHIBITOR | EDUCATIONAL FOUNDATION OF OSAKA MEDICAL AND PHARMACEUTICAL UNIVERSITY (JP) | 2024-08-22 | — | — | US | disclosed |
| WO-2023112440-A1 | VANIN-1 INHIBITOR | 学校法人大阪医科薬科大学 | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240277639-A1 | VANIN-1 INHIBITOR | VNN1, PANK1, VAT1 | VNN1 1/4885CYP3A4 1988/4885CYP2C9 1958/4885 |
| US-12128016-B2 | Vanin-1 inhibitor | VNN1, PANK1, VAT1 | VNN1 1/4885CYP3A4 1988/4885CYP2C9 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.