Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 9/20 | 0.36 |
| ▸ | CTRC | Q99895 | 5/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530249 | 0.92 | F2 (0.37) | MEN1KMT2AF2MMP13P2RX7 | |
| SCHEMBL2527007 | 0.91 | UTS2R (0.34) | MEN1KMT2AF2CTRCPRSS2 | |
| SCHEMBL2529167 | 0.90 | AOC3 (0.36) | MEN1KMT2AMMP13 | |
| SCHEMBL2526963 | 0.90 | MEN1 (0.46) | MEN1KMT2AMMP13P2RX7NPC1 | |
| SCHEMBL2529179 | 0.89 | MMP13 (0.36) | MEN1KMT2AF2MMP13NPC1 | |
| SCHEMBL2525203 | 0.88 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL2528064 | 0.88 | ALDH1A1 (0.39) | MEN1KMT2AF2RAB9A | |
| SCHEMBL2530352 | 0.88 | MMP13 (0.35) | MEN1KMT2AMMP13P2RX7NPC1 | |
| SCHEMBL2531098 | 0.88 | NPSR1 (0.40) | MEN1KMT2AMMP13 | |
| SCHEMBL2528477 | 0.87 | F2 (0.37) | MEN1KMT2AF2MMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | MEN1 1126/4885KMT2A 2317/4885F2 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.