Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22098592 | 0.69 | VNN1 (0.38) | ATM | |
| SCHEMBL14155801 | 0.69 | ATM (0.34) | ATM | |
| SCHEMBL12193292 | 0.69 | ATM (0.34) | ATM | |
| SCHEMBL23126193 | 0.69 | ATM (0.34) | ATM | |
| SCHEMBL22098594 | 0.68 | VNN1 (0.39) | — | |
| SCHEMBL23555243 | 0.67 | ATM (0.33) | ATM | |
| SCHEMBL24352596 | 0.67 | ATM (0.33) | ATM | |
| SCHEMBL18713121 | 0.67 | ATM (0.33) | ATM | |
| SCHEMBL13727484 | 0.66 | CHRNB2 (0.39) | — | |
| SCHEMBL24378705 | 0.66 | ATM (0.32) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204441-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2022046739-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-03-03 | — | — | WO | disclosed |