SCHEMBL25286647

SCHEMBL25286647

CC(C)=CCNc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 7/20 0.71
TAS1R3 Q7RTX0 2/20 0.68
TAS1R1 Q7RTX1 2/20 0.68
P2RY12 Q9H244 2/20 0.67
ADORA1 P30542 3/20 0.66
P2RY2 P41231 2/20 0.66
P2RY1 P47900 2/20 0.66
PRKAB2 O43741 1/20 0.66
TRPM2 O94759 1/20 0.66
LDHA P00338 1/20 0.66
ADRB2 P07550 1/20 0.66
FBP1 P09467 1/20 0.66
SRC P12931 1/20 0.66
PRKAG1 P54619 1/20 0.66
PRKAA2 P54646 1/20 0.66
PDE4D Q08499 1/20 0.66
KCNH2 Q12809 1/20 0.66
PRKAA1 Q13131 1/20 0.66
PDE3A Q14432 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494827 1.00 DNPH1 (0.71) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL29713178 0.94 DNPH1 (0.68) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL29602165 0.94 DNPH1 (0.68) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL29713176 0.93 P2RX3 (0.75) DNPH1TAS1R3TAS1R1P2RY12P2RY2
SCHEMBL18858910 0.93 DNPH1 (0.61) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL18870822 0.93 DNPH1 (0.61) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL16805441 0.93 DNPH1 (0.61) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL18852663 0.93 DNPH1 (0.61) DNPH1TAS1R3TAS1R1P2RY12ADORA1
SCHEMBL18858898 0.92 P2RX3 (0.77) DNPH1P2RY12P2RY2P2RY1TRPM2
SCHEMBL16805447 0.92 P2RX3 (0.77) DNPH1P2RY12P2RY2P2RY1TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404518-B2 Expression of IPT7 from TSS promoter increases root mass and carbon sequestration SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2025-09-02 US disclosed
US-20230203520-A1 EXPRESSION OF IPT7 FROM TSS PROMOTER INCREASES ROOT MASS AND CARBON SEQUESTRATION SALK INSTITUTE FOR BIOLOGICAL STUDIES 2023-06-29 US disclosed