Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246682 | 0.84 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL30486949 | 0.84 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL25287893 | 0.80 | CSNK2A1 (0.45) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL30486964 | 0.78 | MAPT (0.44) | CSNK2A1ALDH1A1KDM4EEGFRTLR7 | |
| SCHEMBL25290653 | 0.78 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL559538 | 0.75 | CSNK2A1 (0.57) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL25252210 | 0.73 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL25293867 | 0.73 | CSNK2A1 (0.52) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL938176 | 0.71 | CSNK2A1 (0.50) | CSNK2A1CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL20509925 | 0.70 | SOS1 (0.50) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |