Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12165831 | 0.81 | MAPT (0.64) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL25246682 | 0.80 | CSNK2A1 (0.43) | KDM4ECSNK2A1ALDH1A1TLR7YTHDC1 | |
| SCHEMBL30486949 | 0.80 | CSNK2A1 (0.43) | KDM4ECSNK2A1ALDH1A1TLR7YTHDC1 | |
| SCHEMBL25287247 | 0.78 | CSNK2A1 (0.43) | KDM4ECSNK2A1ALDH1A1TLR7ADORA1 | |
| SCHEMBL25290653 | 0.78 | CSNK2A1 (0.43) | MAPTKDM4EMEN1KMT2ACSNK2A1 | |
| SCHEMBL25286061 | 0.76 | TLR7 (0.48) | MAPTKDM4ECSNK2A1ALDH1A1TLR7 | |
| SCHEMBL25287893 | 0.73 | CSNK2A1 (0.45) | KDM4ECSNK2A1ALDH1A1TLR7YTHDC1 | |
| SCHEMBL8907091 | 0.72 | APP (0.55) | MAPTKDM4EMEN1KMT2ACSNK2A1 | |
| SCHEMBL13975904 | 0.72 | CYP2D6 (0.61) | TLR7ADORA1 | |
| SCHEMBL15502400 | 0.72 | CYP2D6 (0.61) | TLR7ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |