Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25246682 | 0.82 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1HSD17B10 | |
| SCHEMBL30486964 | 0.78 | MAPT (0.44) | CSNK2A1MAPTTP53PDE5AALDH1A1 | |
| SCHEMBL25287247 | 0.78 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1HSD17B10 | |
| SCHEMBL30486949 | 0.78 | CSNK2A1 (0.43) | CSNK2A1CSNK2A2CSNK2BALDH1A1HSD17B10 | |
| SCHEMBL25287893 | 0.77 | CSNK2A1 (0.45) | CSNK2A1CSNK2A2CSNK2BALDH1A1HSD17B10 | |
| SCHEMBL559538 | 0.73 | CSNK2A1 (0.57) | CSNK2A1TP53CSNK2A2CSNK2BALDH1A1 | |
| SCHEMBL20509925 | 0.72 | SOS1 (0.50) | EGFR | |
| SCHEMBL20509924 | 0.72 | SOS1 (0.50) | EGFR | |
| SCHEMBL29594027 | 0.72 | SOS1 (0.50) | EGFR | |
| SCHEMBL25286061 | 0.71 | TLR7 (0.48) | CSNK2A1MAPTCSNK2A2CSNK2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |