Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.68 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | FOXO3 | O43524 | 1/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.68 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.68 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.68 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.68 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.68 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288386 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25240648 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25238224 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25282131 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25279817 | 1.00 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25289138 | 0.91 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25243968 | 0.91 | ALDH1A1 (0.68) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25681985 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25681948 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL25681916 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TP53HSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114455-A1 | DISCOVERY OF PIPERLONGUMINE AS A NOVEL E3 LIGASE LIGAND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-06-22 | — | — | WO | disclosed |