Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708911 | 0.83 | AKR1C3 (0.39) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL28977344 | 0.81 | ABCB1 (0.38) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL3282414 | 0.80 | NOTUM (0.41) | NOTUMKDM4EMAPTNPC1RAB9A | |
| SCHEMBL28977326 | 0.78 | NOTUM (0.47) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL6551234 | 0.75 | NOTUM (0.37) | NOTUM | |
| SCHEMBL32691742 | 0.74 | NOTUM (0.36) | PTGS1NOTUMKDM4ENPC1RAB9A | |
| SCHEMBL6551232 | 0.73 | NOTUM (0.35) | NOTUM | |
| SCHEMBL28977330 | 0.72 | AKR1C3 (0.46) | AKR1C3AKR1C2AKR1C4PTGS1MTNR1A | |
| SCHEMBL28977349 | 0.72 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1C4PTGS1ABCB1 | |
| SCHEMBL28977348 | 0.72 | CXCL8 (0.39) | AKR1C3AKR1C2PTGS1ABCB1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230213525-A1 | DETECTING MICROBIAL INFECTION IN WOUNDS | QUALIZYME DIAGNOSTICS GMBH & CO KG (AT) | 2023-07-06 | — | — | US | disclosed |