Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578245 | 0.84 | AKR1C3 (0.48) | CXCL8AKR1C3ABCB1AKR1C2PTGS2 | |
| SCHEMBL28977326 | 0.83 | NOTUM (0.47) | CXCL8AKR1C3ABCB1AKR1C2PTGS2 | |
| SCHEMBL28977344 | 0.83 | ABCB1 (0.38) | AKR1C3ABCB1AKR1C2EP300CREBBP | |
| SCHEMBL27999075 | 0.79 | CREBBP (0.48) | EP300CREBBPNPC1RAB9ANOD2 | |
| SCHEMBL28977338 | 0.77 | ABCB1 (0.49) | CXCL8AKR1C3ABCB1AKR1C2PTGS2 | |
| SCHEMBL31432746 | 0.76 | CDC25A (0.55) | CREBBPNPC1RAB9ACDC25A | |
| SCHEMBL17929744 | 0.75 | ALDH1A1 (0.57) | — | |
| SCHEMBL1228227 | 0.75 | CHRM1 (0.37) | NPC1RAB9ANOD2 | |
| SCHEMBL1229480 | 0.74 | CHRM1 (0.39) | NPC1RAB9ANOD2 | |
| SCHEMBL9766071 | 0.73 | KDM4E (0.39) | CXCL8PTGS2PTGS1NPC1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894330-A | Synthesis method and application of 1-acetyl-1H-indol-3-yl acetate derivative | 吉林医药学院 | 2023-04-04 | — | — | CN | disclosed |