Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529449 | 0.90 | CA1 (0.42) | CA1CA2ALDH1A1FDPSATM | |
| SCHEMBL21312412 | 0.90 | CA1 (0.48) | CA1CA2ALDH1A1FDPSATM | |
| SCHEMBL2530893 | 0.89 | CA1 (0.41) | CA1CA2ALDH1A1ATMTSHR | |
| SCHEMBL2531264 | 0.88 | SMN1; SMN2 (0.41) | CA1CA2ALDH1A1FDPSCYP3A4 | |
| SCHEMBL18859460 | 0.88 | ALDH1A1 (0.52) | CA1CA2ALDH1A1FDPSATM | |
| SCHEMBL7218218 | 0.88 | CA1 (0.47) | CA1CA2ALDH1A1FDPSATM | |
| SCHEMBL5458029 | 0.88 | ALDH1A1 (0.52) | CA1CA2ALDH1A1FDPSATM | |
| SCHEMBL2525615 | 0.87 | NAAA (0.44) | CA1CA2ALDH1A1TSHRNAAA | |
| SCHEMBL2523649 | 0.87 | NAAA (0.44) | CA1CA2ALDH1A1TSHRNAAA | |
| SCHEMBL7222715 | 0.86 | CA1 (0.50) | CA1CA2ALDH1A1ATMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |