Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 10/20 | 0.38 |
| ▸ | GSK3B | P49841 | 9/20 | 0.38 |
| ▸ | WNT1 | P04628 | 8/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25301282 | 1.00 | CTSV (0.39) | CTSVCTSLCTSBCTSSKIFC1 | |
| SCHEMBL25248340 | 1.00 | CTSV (0.39) | CTSVCTSLCTSBCTSSKIFC1 | |
| SCHEMBL25295933 | 0.95 | CTSV (0.41) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25295934 | 0.95 | CTSV (0.41) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25291840 | 0.89 | CSF1R (0.41) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25254542 | 0.89 | CSF1R (0.41) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25291841 | 0.89 | CSF1R (0.41) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25814217 | 0.86 | KIFC1 (0.52) | KIFC1CSF1RKITDYRK1AGSK3B | |
| SCHEMBL25297055 | 0.82 | CTSV (0.39) | CTSVCTSLCTSBCTSSCSF1R | |
| SCHEMBL25297054 | 0.82 | CTSV (0.39) | CTSVCTSLCTSBCTSSCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |